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Biological Hazard – Antibiotic resistant Mutant Superbug (Klebsiella pneumoniae): prolific urban distribution | Houston, Texas


ANTIBIOTIC RESISTANCE (03): USA (TEXAS) MULTIDRUG RESISTANT KLEBSIELLA PNEUMONIAE, CG307 PREDOMINANT CLONE
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Published Date: 2017-05-22 22:45:34
Subject: PRO/EDR> Antibiotic resistance (03): USA (TX) MDR K. pneumoniae, CG307 predominant clone
Archive Number: 20170522.5055025

Date: Wed 17 May 2017 3:58 PM ET
Source: NBC News [edited]

A dangerous strain of antibiotic-resistant bacteria is far more common in Houston than anyone knew and shows signs it can spread prolifically, researchers reported [Tue 16 May 2017].

It’s a specific strain of bacteria known as _Klebsiella pneumoniae_. The superbug is showing a special talent for picking up genes that give it the ability to resist a broad range of antibiotics, the team at Houston Methodist hospital system said. “It causes very serious infection in hospitalized patients,” said Dr James Musser, who led the study team. “What we discovered, surprisingly, is one of the major strains causing infection in our patients in Houston is genetically distinct from strains of this same germ causing human infections [elsewhere] in the United States,” Musser added.

Doctors and public health officials have been warning for years about the rise of drug-resistant superbugs. They are especially dangerous to patients in the hospital for extended periods of time but they can also be found in people with ordinary infections such as cystitis and pneumonia.

There have been some nightmarish outbreaks — like one in 2011 at the flagship National Institutes of Health’s clinical center in Bethesda, Maryland, that killed 7 people. That outbreak was caused by a strain of _Klebsiella_ resistant to a major class of antibiotics called carbapenems. Officials eventually discovered it was breeding in the hospital’s sinks. And just this past January [2017], doctors reported on the case of a Nevada woman who had traveled to India and died from a rare superbug that could not be killed by any antibiotic available in the U.S.

Musser’s team did an extended genetic analysis of 1777 _Klebsiella_ samples taken from patients at the 2000-bed Houston Methodist hospital system between 2011 and 2015. They found all sorts of tricks the bacteria had developed to resist antibiotics. That included plasmids — little cassette-like pieces of genetic material that different species of bacteria can swap. They are a very quick and easy way for bacteria to acquire resistance genes and are very worrying to infectious disease experts.

“We identified 15 strains expressing the New Delhi metallo-beta-lactamase-1 (NDM-1) enzyme that confers broad resistance to nearly all beta-lactam antibiotics,” the team reported in the journal mBio, published by the American Society for Microbiology [1].

These extended-spectrum beta-lactamase (ESBL) genes are especially dangerous and often kill patients. A once-rare strain of ESBL _Klebsiella_ called CG307 was unusually common, they found. That may mean there’s more to come, the team warned. “Our results may portend the emergence of an especially successful clonal group of antibiotic-resistant _K. pneumoniae_,” they concluded.

In other words, bacteria are actively trading a toolkit that makes them both deadly and resistant to treatment. The discovery in Houston, a diverse city of 6 million people that’s also a popular destination for people seeking medical treatment, is especially troubling, the researchers noted. The superbug is still around, by the way. “We confirmed that CG307 strains continue to be an abundant cause of infections in our hospital system by sequencing an additional 96 ESBL-producing _K. pneumoniae_ strains recovered in 2017,” the team wrote.

“Currently, unfortunately, there is no approved human vaccine against _Klebsiella pneumoniae_,” Musser said. “We desperately need to have a human vaccine.”

[Byline: Maggie Fox]

[1. Long SW, Olsen RJ, Todd N. Eagara TN, et al. Population Genomic Analysis of 1777 Extended-Spectrum Beta-Lactamase-Producing _Klebsiella pneumoniae_ Isolates, Houston, Texas: Unexpected Abundance of Clonal Group 307. mBIO 2017; 8(3). Published 16 May 2017. Available online at: http://mbio.asm.org/content/8/3/e00489-17.full. ]


Communicated by:
ProMED-mail
<promed@promedmail.org>

[The following is the edited abstract from the journal article referenced in the news report above:

Abstract
——–
_Klebsiella pneumoniae_ is a major human pathogen responsible for high morbidity and mortality rates. The emergence and spread of strains resistant to multiple antimicrobial agents and documented large nosocomial outbreaks are especially concerning. To develop new therapeutic strategies for _K. pneumoniae_, it is imperative to understand the population genomic structure of strains causing human infections.

To address this knowledge gap, we sequenced the genomes of 1777 extended-spectrum beta-lactamase-producing _K. pneumoniae_ strains cultured from patients in the 2000-bed Houston Methodist Hospital system between September 2011 and May 2015, representing a comprehensive, population-based strain sample. Strains of largely uncharacterized clonal group 307 (CG307) caused more infections than those of well-studied epidemic CG258. Strains varied markedly in gene content and had an extensive array of small and very large plasmids, often containing antimicrobial resistance genes. Some patients with multiple strains cultured over time were infected with genetically distinct clones.

We identified 15 strains expressing the New Delhi metallo-beta-lactamase 1 (NDM-1) enzyme that confers broad resistance to nearly all beta-lactam antibiotics. Transcriptome sequencing analysis of 10 phylogenetically diverse strains showed that the global transcriptome of each strain was unique and highly variable.

Experimental mouse infection provided new information about immunological parameters of host-pathogen interaction. We exploited the large data set to develop whole-genome sequence-based classifiers that accurately predict clinical antimicrobial resistance for 12 of the 16 antibiotics tested. We conclude that analysis of large, comprehensive, population-based strain samples can assist understanding of the molecular diversity of these organisms and contribute to enhanced translational research.

[The above was extracted from the full article, which is available at the source URL. – Mod.ML]

_Klebsiella pneumoniae_ are Gram-negative bacteria that can cause healthcare-associated infections, including pneumonia, urinary tract infections, bloodstream infections, wound or surgical site infections, and meningitis. They spread from patient to patient via contact with the contaminated hands of healthcare personnel or contaminated environmental surfaces. Patients at most risk are those who require mechanical ventilators or intravenous catheters, and patients who are taking long courses of antibiotics.

_K. pneumoniae_ have become increasingly multidrug resistant. The development of multiple-drug resistance allows _K. pneumoniae_ to persist in the hospital environment, in which antibiotic usage is widespread. Multidrug-resistant (MDR) _K. pneumoniae_ isolates frequently produce extended-spectrum β-lactamases (ESBLs) and/or carbapenemases in combination with quinolone and aminoglycoside resistance.

ESBLs are frequently plasmid-encoded beta-lactamases that hydrolyze extended-spectrum cephalosporins with an oxyimino side chain (cefotaxime, ceftriaxone, and ceftazidime), as well as the oxyimino-monobactam aztreonam. ESBLs also confer resistance to penicillins and older cephalosporins, but do not confer resistance to the carbapenems. However, _K. pneumoniae_ have also developed resistance to carbapenem antibiotics by the acquisition of certain transmissible plasmid-encoded beta-lactamases (carbapenemases) that destroys the carbapenems, as well as most other beta-lactam antibiotics. These organisms are named Klebsiella pneumoniae carbapenemase (KPC)-producers.

Because transmissible resistance plasmids can be shared between _Klebsiella_ spp. and other pathogens, these enzymes now been identified in several other species in the Enterobacteriaceae family and are called carbapenem-resistant Enterobacteriaceae or CRE.

Molecular typing procedures, such as multilocus sequence typing (MLST) and whole genome sequencing, have been used to classify _K. pneumoniae_ into ST and clonal groups (CG). The above investigation sequenced the genomes of 1777 ESBL-producing _K. pneumoniae_ strains cultured from patients in the 2000-bed Houston Methodist Hospital system between September 2011 and May 2015. The study found that CG307, an otherwise unusual clonal group caused more infections, for unknown reasons, in the Houston, Texas region throughout the study period (between September 2011 and May 2015), as well as in 2017, than CG258 that predominates elsewhere in the U.S. (http://aac.asm.org/content/53/8/3365.full). The study also found that 64.6 percent of the CG258 strains compared to 34.3 percent of the CG307 strains were KPC-producers and CG307 strains causing infections in Houston appeared to be as virulent as CG258 strains. – Mod.ML

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/245.]

See Also

Antibiotic resistance (02): WHO, priority pathogens 20170301.4871299
Antibiotic resistance (01): China: colistin, MCR-1 clin. Enterobacteriaceae isolates 20170129.4799871

2016
—-
Carbapenem-resistant Enterobacteriaceae – Ireland: (LK) nosocomial, fatal, 2009-2015 20161124.4652418
Antibiotic resistance (04): India, China, environmental pollution 20161020.4574059
Antibiotic resistance (03): India (TG) environmental pollution 20161010.4548738
Antibiotic -resistant Enterobacteriaceae – USA: (CA) reportable 20161008.4545844
Gonococcal disease – USA (05): (HI) ceftriaxone plus azithromycin resistance 20160924.4513277
Antibiotic resistance (02): UN General Assembly 2016, WHO Global Action Plan 20160923.4511617
Antibiotic resistance: International Journal of Infectious Diseases, editorial 20160918.4497194
Antibiotic resistance – USA (06): ESBL, FQ, E. coli, UTI 20160918.4496481
Antibiotic resistance – France: non-MCR-1, colistin/carbapenem, 2014 20160916.4492825
Antibiotic resistance – USA (05): colistin, MCR-1, E. coli, new case, contacts 20160911.4479863
Gonococcal disease – UK (02): azithromycin resistance, spread, MSM, RFI 20160910.4479782
Antibiotic resistance, Salmonella – USA: NARMS, 2014 20160910.4478868
Antibiotic resistance – USA (04): (NJ) colistin/carbapenem, MCR-1, E. coli, human 20160902.4459453
Antibiotic resistance – Europe, Canada: colistin, MCR-1, E. coli, bovine, human 20160808.4400601
Antibiotic resistance – Germany: colistin, MCR-1, E. coli, poultry, 2010 – 2015 20160728.4374873
Gonococcal disease – USA (03): increasing azithromycin resistance, 2014 20160716.4349791
Antibiotic resistance – Belgium: colistin, MCR-2, plasmid, E. coli, pigs, calves 20160709.4335297
Antibiotic resistance – Portugal: colistin, MCR-1, Salmonella, Cu tolerance 20160703.4323241
Antibiotic resistance – USA (03): (NY) colistin, MCR-1, E. coli, human 20160630.4317770
Antibiotic resistance – multicountry: colistin, MCR-1, E. coli, gull 20160630.4313655
Antibiotic resistance, Salmonella – Africa: (sub-Saharan) fluoroquinolones 20160617.4293589
Antibiotic resistance – USA (02): colistin, MCR-1, E. coli, pig 20160616.4290293
Antibiotic resistance – USA: colistin, MCR-1, E. coli, human, pig 20160528.4251552
Antibiotic resistance – Denmark: AR genes, archived soil, 1923-2010 20160224.4047676
Antibiotic resistance – Italy: colistin, MCR-1, E. coli, turkeys, 2014 20160113.3933461
Antibiotic resistance – Canada: colistin, MCR-1, E. coli, grd. beef, human, 2010 20160106.3915891
Gonococcal disease – UK: (England) azithromycin monotherapy resistance, RFI 20160103.3907866
………………………………………….sb/ml/ec/lm

Source:
A ProMED-mail post
ProMED-mail is a program of the International Society for Infectious Diseases

Related:

Researchers in Belgium identify novel colistin-resistance gene

Public Release: 23-Jul-2015 | Research suggests retail meat is a potential vehicle for disease-causing Klebsiella

The Proper Abuse of Political Correctness …


New Orleans, Louisiana — Now Enter at Your Own Risk!

Lessons From New Orleans

A New Orleans Heritage removal site

A New Orleans Heritage removal site Image: Lessons From New Orleans

A New Orleans Heritage removal site

A New Orleans Heritage removal site. Image: Lessons From New Orleans

The New Orleans, Louisiana mayor emulates an ISIS mentality as he has historical heritage markers and monuments removed and discarded by masked individuals, under guard, and in some cases during the middle of the night, without any voter referendum, because his edict now claims them and their historical significance  to be regarded as a pubic nuisance. The images above portray the non-inclusive replacements he is providing for brave tourist and/or citizens to view, that are daring enough to visit this crime ridden, politically corrected, democrat managed, historically revised hell hole that was once a great culturally diversified Southern U.S. city.

Indeed, “… one should carefully judge the symbol in the context in which it appears.”

So then, when it comes down to celebrating other people’s heritage and history, they can all just go to hell…. is that what you are telling us?

Celebrating Perversity


“New York Times has more sympathy for a democrat child molester than his victims.”

In fighting for the right to molest children, …“There’s a sadness for the loss of a (dysfunctional lifestyle advocate and attention whore) leader who has put himself on the front line of many of these (homosexual) causes that have been so important to us…”

Related: 4th accuser says Seattle mayor paid him for sex

First they told us homosexuality was normal, contrary to natural law
Then they claimed transgenderism was the new normal.
Now they are attempting to convince us to normalize pederasty.
Should we be concerned about our animals being next?

The connection between homosexuality and pederasty is well documented in scientific literature and crime statistics. The Seattle mayor is but another example. Male homosexuals, having no womb; this is how they reproduce themselves.

Besides, would calling one member of a LGBTQ couple “husband” not be considered a “heteronormative” thought crime by that irrational segment of a society?


Flashback:

In 2014, the National Health Interview Survey, which is the government’s premier tool for annually assessing Americans’ health and behaviors, found that 1.6 percent of adults self-identify as gay or lesbian, and 0.7 percent consider themselves bisexual.

The overwhelming majority of adults, 96.6 percent, labeled themselves as straight in the 2013 survey. An additional 1.1 percent declined to answer, responded “I don’t know the answer” or said they were “something else.”

CDC: Less than 3 percent of the U.S. population identify themselves as gay, lesbian or bisexual, the Centers for Disease Control and Prevention reported Tuesday in the first large-scale government survey measuring Americans’ sexual orientation.  Are they insinuating it is a “Social Disease?”  Perhaps like “gun violence?”  Or maybe it’s just a “Sport.”

——-

Meanwhile, The Obama administration’s priorities were on display yesterday (May 17, 2014).  Weasel Zippers noticed that now ex-President Obama and a number of United States embassies commemorated ‘International Day Against Homophobia Or Transphobia’ while ignoring Armed Forces Day on Twitter.


… the more familiar people are with the concepts of thought control and menticide, the more they understand the nature of the propaganda barrage directed against them, the more inner resistance they can put up, even though inevitably some of the inquisitor’s suggestions will leak through the barrier of conscious mental defense.

–“The Rape of the Mind: The Psychology of Thought Control, Menticide, and Brainwashing” (1956)., Joost A. M. Meerloo, M.D.,

Fatal “Political correctness” and ‘Folks Who Want to Cause Mischief’ strike again…Terrorist suicide bomber in need of understanding suspected.


Headlines: Human-caused Health Threat – UK Terrorist Attack

(London’s Islamist mayor) Sadiq Khan FINALLY responds to London terror attack after being slammed for ‘silence’

Flashback: Sadiq Khan: London’s Muslim mayor says terror attacks ‘part and parcel’ of living in a major city.

Manchester incident: Latest updates [BBC]

Manchester Arena explosion: 19 killed in ‘terror attack by suicide bomber’ at Ariana Grande concert

At Least 19 Killed in Possible Suicide Blast at Manchester Arena Concert Featuring Ariana Grande

Manchester Arena explosion at Ariana Grande gig kills 19 and injures 50 as cops swarm to treat wounded concertgoers

“This is the lesson we have to learn, that of the two types of courage, that which consists in living is greater than that which aims at dying. We have to learn that sacrifice of one’s life, though it may be a necessary means to an end, is not an end in itself. As a free people, we must choose the affirmative courage of life, not the negative sacrifice of death.” –A.M. Meerloo, Total War and the Human Mind, 1944.

It is profoundly likely that the psychopathic perpetrator(s) of this event have a very high Mohammad coefficient, and believe no one is so secure or safe from a dedicated jihadist willing to die in the commission of their deeds of insanity.

They “believe in belief” — they themselves don’t always even believe, but want others to believe (or be put to death).

See Also

Neo-Nazi Converts to Islam, Slaughters Friends for Disrespecting Faith

Don’t forget there will also be a Mjölnir effect ….


“… one should carefully judge the symbol in the context in which it appears.”

NAACP fires its president, will embrace Black Lives Matter (Most)

The National Association for the Advancement of Colored (Lives Matter Most) People (NAACP), the 109 year old civil rights organization, will not renew the contract of its president, Cornell Brooks, and will “recast” its mission by conducting “a systemwide and strategic revisioning process that will ensure that the NAACP can address these 21st century challenges.”

Reading between the lines isn’t difficult; the NAACP will become more like Black Lives Matter (Most) and less like a mainstream organization dedicated to advancing the economic interests of blacks.

Reuters:

Russell said the process might take a year, during which the group’s board would gather comment from members nationwide about the NAACP’s future course.

The NAACP has been a leader of U.S. civil rights since its founding in 1909. Its pre-eminence has been challenged by the Black Lives Matter (Most) movement that sprang up to protest police shootings of African Americans in recent years and by mass protests against President Donald Trump.

Johnson said the group wanted to strengthen local and state activism and education and develop local leadership.

The decision not to renew Brooks’ contract was made by the NAACP national board on Friday.

“I’m disappointed and mystified,” Brooks said in a telephone interview. He said that, including interim leaders, he was at least the 10th head of the NAACP in 15 years.

“There’s been a revolving door of CEOs at the NAACP and this is a bad moment for it to be spinning,” he said.

The NAACP had tried to keep the violent radicals of Black Lives Matter (Most) at arms length – tapping into the energy of their activism without embracing their agenda. But it became clear that younger blacks preferred the confrontational methods of BLM(Most) and it became a question of adopting the radical agenda of BLM(Most) or becoming less relevant in the black community.

Any “revisioning” of the NAACP will be led by radicals who don’t care as much about improving the lives of black people as they do pushing their hysterically exaggerated notions of “justice” and “police brutality.” The NAACP tried to work through the courts and the Justice Department to hold police accountable. BLM(Most) wants to take to the streets to threaten violence to get what they want. This is not a subtle shift but a radical departure for an organization that, for more than 100 years, has fought for civil rights within the mainstream of American politics.

But the times have changed. And younger blacks prefer the “activism” and rhetoric of violent revolution. I don’t think it’s an exaggeration to say that we are about to enter a new phase in race relations in the US with unknown consequences for black and white alike.

[Byline Rick Moran]

21 May 2017
American Thinker (edited)

Welcome the new radical Leftist carpetbaggers, Racial extortionists, and their Black Klux Klan.


Civil wars end when one side is forced to accept the authority of the other. The left expects everyone to accept its ideological authority. Conservatives expect the left to accept Constitutional authority. The conflict is still political and cultural. It’s being fought in the media and within the government. But if neither side backs down, then it will go beyond words as both sides give contradictory orders.

The left is a treasonous movement. The Democrats became a treasonous organization when they fell under the sway of a movement that rejects our system of government, its laws and its elections. Now their treason is coming to a head. They are engaged in a struggle for power against the government. That’s not protest. It’s not activism. The old treason of the sixties has come of age. A civil war has begun.

This is a primal conflict between a totalitarian system and a democratic system. Its outcome will determine whether we will be a free nation or a nation of slaves.

Daniel Greenfield

The Circus of the Absurd, Cultification and Folie à plusieurs


Democrats in the Cesspits of Despair


Psychological decompensation refers to the loss of mental stability and self-control due to the failure of overtaxed coping mechanisms to handle stress.  The term decompensation is typically applied to breakdowns in individuals who are psychologically fragile in the first place.  For minds burdened with a fallacious self-image, unrealistic life expectations, or a distorted view of reality, heightened stress overwhelms the already brittle ego defenses, and raw psychic pain and rage flows unrestrained.


I have an answer for the Instapundit’s favorite question: “Why is the Democratic Party such a cesspit of hypocrisy?” in two words: “disconfirmatory reality,” meaning the failure of reality to conform to their beliefs. This leads to all sorts of mischief and worse.

Last week, revered left wing thinker Noam Chomsky said that President Trump and the Republican Party represent a worse threat to humanity than ISIS; NBC news reader Lester Holt interrupted the President of the United States nine times in three minutes; some art professor announced that Republicans in Congress should be lined up and shot; and exactly none of the mainstream media players, from the New York Times to CBS and the Huffington Post, all of which had spent weeks enthusiastically berating Sarah Palin for suggesting the Republicans target a few House districts for election purposes protested repeated calls for Trump’s assassination or saw anything wrong with any of the rest of it.

This behavior stands in stark contrast to what Republicans do when they lose elections: no serious conservative, for example, advocated that Obama be shot; tea party gatherings never turned into riots; and even fringe right wing sites generally talk more about issues than personalities.

So why are Democrats such hypocrites? Remember, they’re the party of liberal progressivism: the party that inveighs endlessly against racism but embraces eugenics, spawned the KKK, and rewards people like Al Sharpton; the party that accuses its enemies of Nazism but embraces the Moslem Brotherhood and accepts both funding and direction from the only self confessed and unrepentant Nazi in American politics; the party that sees working Americans as deplorable embarrassments to their own enlightened community for their imagined illiteracy, homophobia and misogyny but reflexively defends Islam’s right to enslave a billion women and stone deviants in the public square; and the party that fervently believes all forms of socialism morally better than the Christian ethos built into the American Constitution despite socialism’s unbroken record of devolution to mass murder, social stagnation, and the effective enslavement of more than 99% of the people by less than 1%.

When Leon Festinger and his associates undertook the work leading to their widely misunderstood and maligned theory of cognitive dissonance, their ultimate goal was to understand how forty million decent Germans and tens of millions in the rest of Europe could so enthusiastically support Nazi methods — and it’s their research on how cult members react to the unequivocal disproof of some central belief that’s important today — because the increasing calls among Democrats for violence shows that same process at work here as in Germany of the 1930s.

In brief, what happens when events disprove a cult’s major belief is that some adherents drop out; a majority first reshape their vision of reality to accommodate both their belief and an edited version of reality and then either gradually fade out of the cult or double down on their efforts to find confirmatory opinion by compromising others; and, a few set out to force others to act as if the belief stands unchallenged.

Among the last group, the nature and duration of the disproof process matters: the more abrupt and final the disproof, the more violent the reaction — leading, in the extreme, to Jonestown events in which mothers murder their own children rather than face reality. Where that disproof is gradual and cumulative, however, the extreme group both grows as some majority members find social support by edging into the extremist camp, and loses its inhibitions against the organizational use of dishonesty, crime, and violence at roughly the rate at which the belief loses market share in the society they either belong or aspire to — a classic slippery slope political and media players are particularly susceptible to because the pre-existing professional community amplifies their ability to provide their own social support while shutting out contrary voices.

The key elements that have to be in place for the true believers to slide toward dishonesty and violence are personal commitment to the belief, undeniable disproof, and enough rationality for the person to know that the belief has been disproven.

That two of these are in place with the Trump victory deniers is obvious: most of the journalists and others now attacking Trump in particular and Republicans in general have overwhelming and long term commitments to the progressive cause. This despite the fact that every major attempt to act on those beliefs, whether by Uncle Joe, Chairman Mao, the Kim Dynasty in North Korea, or that great hero and champion of the poor, Hugo Chavez, has turned into a murderous regime corrupting everyone and everything it touched.

Whether most of these people are rational enough to comprehend the truth that they can’t acknowledge is a much more difficult question, in part of course because they can’t be rational on the subject.  But the fact that they generally don’t apply their beliefs to themselves suggests that most have at least some grasp of their falsity. So far, for example, the number of dedicated leftists in politics and the media who have voluntarily gone to Cuba, Canada, or a V.A. hospital for superior health care remains, like the number voluntarily paying higher total taxes or offering lands and beaches they own for windfarm development, as close to zero as it is possible to get.

Thus the behavioral explanation for the fact that conservatives will generally accept electoral defeat gracefully whereas Democrats eagerly embrace hypocrisy, corruption, dishonesty and even violence to continue the fight by any means necessary is simply this: reality supports conservative belief, but pushes leftists down the slippery slope to the insanity of Trump derangement syndrome.  Reality forces them to continually choose between recognizing the emptiness and historical absurdity of their core beliefs or holding themselves hostage to those beliefs by escalating their commitment, no matter what foul means may be required to make reality conform to their fantasy.

[Byline Paul Murphy]

21 May 2017
American Thinker (edited)

Related

The Mass Media Cult Goes Pathological

The Democrats Do the Hokey-Pokey

Maxine Waters just can’t shut up

See Also

Shared Psychotic Disorder

Grifters and then some …


Dolce vita! The Obamas arrive in Tuscany on a private plane escorted by six fighter jets and a 13-car motorcade for five days in a $15k-a-night private villa

Barack and Michelle Obama flew into a Tuscany militray base on Friday, escorted by six fighter jets

They were escorted in a 13-car motorcade to Borgo Finocchieto, a refurbished 14th century village

The five-building, six-acre space is owned by Obama’s former ambassador to Italy, John Philips

It features 22 bedrooms, multiple saunas and Jacuzzis, a swimming pool, a gym and a basketball court 

It’s also surrounded by beautiful rolling hills that can be explored by car, helicopter or even hot air balloon

The Obamas, who have been on multiple vacations since leaving the White House, will reportedly visit Florence and Siena during their vacation

Read more …

————

The Obamas, have been on multiple vacations since leaving the White House, they will reportedly visit Florence and Siena during their (extended) vacation.

An international perspective: “Such a despicable couple! They disgraced America and are now on permanent vacation.”

So, who is paying for all of this?  Follow the money…